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Abstract #2424

Multi-Coil Metabolic Imaging, with SENSE Reconstruction, of Hyperpolarized [1-13C] Pyruvate in a Live Rat at 3.0 T

James Tropp1, Albert Chen2, Janine Lupo3, Paul Calderon4, Thomas Grafendorfer5, Don McCune6, Fraser Robb6, Yi-Fen Yen7, Peder Larson3, Robert Bok3, Simon Hu3, Rolf Schulte8, Dan Vigneron3, Ralph Hurd7, Sarah Nelson3

1Applied Science Laboratory, GE Healthcare, Femont, CA, USA; 2Applied Science Laboratory, GE Healthcare, Toronto, Ontario, Canada; 3Radiology, UCSF, San Francisco, CA, USA; 4Engineering, GE Healthcare, Femont, CA, USA; 5Engineering, GE Healthcare, Menlo Park, CA, USA; 6Engineering, GE Healthcare, Aurora, OH, USA; 7Applied Science Laboratory, GE Healthcare, Menlo Park, CA, USA; 8MR, GE Healthcare, Garching bei Muenchen, Germany


We present multi-channel metabolic images of of hyperpolarized [1-13C] Pyruvate in the live rat, with full k space and reduced field of view acquisition with SENSE reconstruction, showing good correlation with anatomic (proton) images taken in the same exam, without moving the animal.