Alexander Fuchs1, Susanne Heinzer-Schweizer1, Anke Henning1, Peter Boesiger1
1Institute for Biomedical Engineering,
University and ETH Zurich, Zurich, Switzerland
A fundamental requirement to use spectroscopy in a clinical setting is the ability to reliably quantify the individual metabolites. While 2D experiments like JPRESS can provide improved spectral separation by dispersing spectral information in an additional frequency dimension the artificially injected ERETIC signal can serve as a stable and well known reference signal. It is shown that the ERETIC reference signal can be readily incorporated into in-vivo 2D spectroscopic experiments, which finally provides the necessary premises for reliable quantification in in-vivo 2D MRS.