Eugene Ozhinsky1,2, Sarah J. Nelson1,3
1Surbeck Laboratory of Advanced Imaging, Department of Radiology, University of California, San Francisco, San Francisco, CA, USA; 2UCSF/UCB Joint Graduate Group in Bioengineering, University of California, San Francisco, San Francisco, CA, USA; 3Program in Bioengineering, University of California, San Francisco, San Francisco, CA, USA
Current MRSI protocols require placing a small selected volume (PRESS box) that does not extend past the edges of the brain to avoid artifacts from the subcutaneous fat and sinuses. This significantly limits the area where tumors can be detected. Manual prescription of an MRSI exam is time-consuming and requires operator training, resulting in limited adoption of MRSI in clinical setting, despite significant advantages in it's diagnostic ability. The goal of this project is to develop a technique to automatically prescribe an MRSI exam, while maximizing the coverage of the brain.