Dennis Klomp1, Cecilia Possanzini2, Bart van de Bank1, Vivian Timmers2, Alexander Raaijmakers3, Vincent Boer1, Peter Luijten1
1Radiology, University Medical Center Utrecht, Utrecht, Netherlands; 2Philips Medical Systems, Best, Netherlands; 3Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands
MRS of the human breast is challenging, especially when tumor sizes are small and substantial lipid contents are included in the suspected voxel. At 7T, the sensitivity may improve, but due to expected non uniformities in B1 fields, lipid suppression becomes even more challenging. In this study we demonstrate the use of a B1 optimized RF coil in combination with a semi LASER sequence with MEGA water and lipid suppression to enable the detection of ultra low concentrations of choline pools in vivo.