Yan Zhang1, Stefano Marenco1, Jun Shen1
1National Institute of Mental Health, Bethesda, M D, USA
A method for measuring glutamate using a single echo time without employing any spectrally selective pulses at 3 Tesla was proposed. By adding an additional slice-selective refocusing pulse into the PRESS sequence and optimizing echo time and inter-pulse delays, glutamate editing can be achieved in a single shot without using spectrally selective pulses which are susceptible to B0 inhomogeneity.