Combined Proton and HP 3He Oxygen Partial Pressure Mapping for the Evaluation of Acute Respiratory Distress Syndrome

Elise Bannier¹, Katarzyna Cieslar¹, Sophie Gaillard¹, Abdulrazzaq Sulaiman¹, Emmanuelle Canet-Soulas¹, Yannick Crmillieux¹

Acute Respiratory Distress Syndrome (ARDS) can result from multiple factors such as pulmonary infection, gas inhalation or drowning. In this work, proton and hyperpolarized 3He MRI were applied in a rabbit model of ARDS. Alteration of ventilation and gas exchange were observed and quantified using both oxygen partial pressure and oxygen depletion rate maps and compared to inflammation extent on proton images.