Abstract #2190

Hyperpolarized Helium-3 Ventilation and ADC MR Imaging in the Treatment of Patients with Inoperable Lung Cancer.

Jaime Mata¹, Ke Sheng², Jing Cai², Paul Read², Talissa Altes¹, Eduard de Lange¹, Klaus Hagspiel¹, William Tobias³, Gordon Cates³, James Brookeman¹, John Mugler III¹

¹Radiology, University of Virginia, Charlottesville, VA, USA; ²Radiation-Oncology, University of Virginia, Charlottesville, VA, USA; ³Physics, University of Virginia, Charlottesville, VA, USA

Non-small-cell carcinoma alters the regional anatomy and physiology of the lung. Our purpose was to investigate, using hyperpolarized (hp) He-3, the regional ventilatory and structural pulmonary changes in patients with inoperable lung carcinoma.