Abstract #2182

Abnormal Ventilation Assessed with Hyperpolarized 3He MRI in Young Cystic Fibrosis Patients with Normal Lung Function. Evaluation of Immediate Influence of a Single Chest Physiotherapy Session.

Elise Bannier¹, Katarzyna Cieslar¹, Karim Mosbah¹, Francoise Aubert², Francois Duboeuf¹, Zahir Salhi³, Sophie Gaillard¹, Yves Berthezne¹, Philippe Reix⁴, Yannick Crmillieux¹

¹Universit de Lyon, CREATIS LRMN, Lyon, France; ²Centre d'Investigation Clinique, Lyon, France; ³Johannes Gutenberg Universitt, Mainz, Germany; ⁴Service de Pdiatrie, Hpital Femme Mre Enfant, Lyon, France

The aim of the study was to assess the ability of 3He MRI to detect lung ventilation abnormalities in pediatric patients with normal pulmonary function tests (PFT) and to observe the immediate effect of a single chest physiotherapy session (CPT). Ventilation defects were observed and quantified pre and post CPT.