Quantification of Hepatic Perfusion Fraction Using Diffusion-Weighted Imaging with Multiple B-Values: Utility for the Diagnosis of Liver Cirrhosis

Jignesh Patel¹, Eric Sigmund¹, Jens Jensen¹, Henry Rusinek¹, Marcel Oei¹, Bachir Taouli¹

In this study we have prospectively quantified advanced liver diffusion parameters including perfusion fraction, and diffusion coefficient using higher b-values (ADC High) in patients with liver cirrhosis and normal liver. Perfusion fraction was significantly lower in liver cirrhosis, demonstrating its potential utility for the diagnosis of cirrhosis.