Abstract #1699

Acute Blockade of 5HT2a Receptors Reduces Orbitofrontal Cortex Response to Angry and Fearful Faces

Bettina Hornboll^1,2, Jon S. Wegener^1,2, Olaf B. Paulson^1,2, James B. Rowe^2,3, Gitte Moos Knudsen^2,4, Hartwig Siebner^1,2, Julian Macoveanu^1,2

¹Danish Recearch Center for MR, Copenhagen University Hospital, Hvidovre, Hvidovre, Denmark; ²Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark; ³Department of Clinical Neurosciences, Cambridge University, Cambridge, UK; ⁴Neurobiology Research Unit,, Copenhagen University Hospital, Copenhagen, Denmark

In 17 healthy volunteers, we used pharmacological functional MRI to