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Abstract #1656

Mapping Functional Connectivity in the Anesthetized Rat Using CBV Vs BOLD

Matthew Evan Magnuson1, Waqas Majeed1, Shella Keilholz1

1BME, Georgia Institute of Technology/ Emory University, Atlanta, GA, USA


Low frequency fluctuations in the resting state BOLD signal are commonly used to map functional connectivity in the rat brain. CBV weighted fMRI can provide increased sensitivity and spatial resolution as compared to BOLD fMRI. However, few resting state functional connectivity studies using CBV have been conducted, and no direct comparisons have been made between functional connectivity measurements made with CBV and BOLD in rats. In this study we compare cross correlation values and low frequency power spectral properties of CBV and BOLD.