Essa Yacoub1, Kmil Ugurbil2, Cheryl A. Olman1
1Center For Magnetic Resonance Research, University of Minnesota, Minneapolis , MN, USA; 2Center For Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, USA
Studying layer-dependent neural activity is important because in all species cells, cortical afferents and projection neurons are arranged with reference to different depths in the gray matter. The investigation of layer specific functional activation in humans has been demonstrated at 3 T. Differential layer specific activation has not been demonstrated in any model. High field magnets have proven beneficial for fMRI with respect to spatial specificity and functional sensitivity, offering significant advantages over lower fields. In this work we demonstrate the potential of high field fMRI to observe layer specific activations as well as possible changes in these activations.