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Abstract #1509

Delayed Arrival of Arterial Blood Measured with Arterial Spin Labeling in Patients with a Symptomatic Carotid Artery Stenosis

Reinoud Pieter Harmen Bokkers1, H. Bart van der Worp2, Willem P. Mali1, Jeroen Hendrikse1

1Department of Radiology, UMC Utrecht, Utrecht, Netherlands; 2Department of Neurology, UMC Utrecht, Utrecht, Netherlands


Arterial spin labeling (ASL) with image acquisition at multiple delay times is able to measure the temporal dynamics of arterial blood inflow in addition to cerebral blood flow. The purpose of this study was to investigate the effect of a symptomatic stenosis in the internal carotid artery on the arrival of arterial blood measured with ASL. Herein, we found a delayed arrival of arterial blood in the hemisphere ipsilateral to ICA stenosis. ASL measurements of arterial blood inflow may provide valuable information on the hemodynamic changes in patients with an ICA stenosis.