Jonathan D. Clayden1, Zoltan Nagy2, Daniel C. Alexander3, Chris A. Clark1
1Institute of Child Health, University College London, London, England, UK; 2Wellcome Trust Centre for Neuroimaging, University College London, London, England, UK; 3Department of Computer Science, University College London, London, England, UK
This work describes a process for optimising both Stejskal-Tanner and dual spin-echo diffusion weighted EPI sequences, for the specific purpose of estimating axon radius or other microstructural properties of white matter. The dual spin-echo sequence is optimised with and without eddy-current nulling. We compare the sequences' suitabilities for estimating axon radius, and demonstrate their ability to recover radius information, even with modest gradient strength and SNR.