Rebecca Sara Samson1, Mark R. Symms2, David L. Thomas3, Madhan Kolappan1, David H. Miller1, Claudia A M Wheeler-Kingshott1
1Department of Neuroinflammation, UCL Institute of Neurology, London, UK; 2Department of Clinical & Experimental Epilepsy, UCL Institute of Neurology, London, UK; 3Medical Physics & Bioengineering, UCL, London, UK
There are several technical challenges associated with studying the optic nerve (ON) using DTI, in particular its small size, motion, contamination of signal by fat and Cerebrospinal Fluid (CSF), and susceptibility effects pose significant problems. We present our preliminary experiences with the implementation of ON DTI on two different manufacturers 3.0T scanners using different data acquisition methods both with and without the use of parallel imaging.