Absolute Quantification of Phosmomono- And Phosphodiesters in the Brain of Patients with Major Depression

Wolfgang Weber-Fahr¹, Helga Wentzel, Traute Demirakca¹, Alexander Sartorius¹, Gabriele Ende¹

The phospholipd metabolism in a group of 18 patients and 22 matched controls was investigated with 31P-MRS. We used a 3D-whole head RINEPT Sequence together with point-spread function (PSF) corrected tissue segmentation for robust absolute quantification.