Adrienne Nicole Dula1,2, Siddharama Pawate3, E B. Welch1,4, Robin G. Avison1, Subramaniam Sriram3, Jeff L. Creasy2, John C. Gore1,2, Malcolm J. Avison1,2
1Institute of Imaging Science, Vanderbilt University, Nashville, TN, USA; 2Radiology and Radiological Sciences, Vanderbilt Medical Center, Nashville, TN, USA; 3Neurology and Immunology, Vanderbilt Medical Center, Nashville, TN, USA; 43MR Clinical Science, Philips Healthcare, Cleveland, OH, USA
The goal of the present study was to assess the potential for 7T neuroimaging of MS, with particular emphasis on improving conspicuity of MS pathology not previously observed by MRI at lower fields. The course of MS is highly variable and better markers of disease activity and response to therapy are needed. In addition to the pathology revealed by MRI at 1.5 and 3T, ultra-high field MRI also reveals cortical and perivascular MS lesions that reflect different aspects of MS neuropathology.