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Abstract #1101

Global ROI-Based Functional Connectivity MRI (FcMRI) Analysis for Classification of Alzheimers Disease

Shi-Jiang Li1, Barney Douglas Ward1, Piero Antuono2, Zhilin Wu1, Jennifer Jones2, Mei-Jie Zhang3

1Biophysics, Medical College of Wisconsin, Milwaukee, WI, USA; 2Neurology, Medical College of Wisconsin, Milwaukee, WI, USA; 3Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, USA


In contrast to the traditional approach of examining functional connectivity for a few, prespecified, ROIs, we performed a global functional connectivity analysis by considering all ROI pairs from a large ensemble of anatomically predefined ROIs to determine classification of Alzheimers disease.