Abstract #0964

In-Vivo Quantification of the Hippocampal Subfields Using 4.7T Fast Spin Echo Imaging

Nikolai Vladimirovich Malykhin^1,2, Robert Marc Lebel¹, Nicholas J. Coupland³, Rawle Carter³, Peter Seres¹, Alan H. Wilman¹

¹Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada; ²Centre for Neuroscience, University of Alberta, Edmonton, Alberta, Canada; ³Psychiatry, University of Alberta, Edmonton, Alberta, Canada

Changes in the hippocampus have often been implicated to the pathophysiology of many neurological and psychiatric diseases. Current MRI studies measure global hippocampal atrophy instead of measuring volume loss in its subfields. The purpose of this study was to delineate and quantify the hippocampal subfields in-vivo within entire hippocampal structure using ultra-high resolution Fast Spin Echo (FSE) imaging at 4.7T.