Dingxin Wang1, Ron Gaba2, Robert Lewandowski2, Robert Ryu2, Kent Sato2, Mary Mulcahy3,4, Riad Salem2,4, Reed Omary1,4, Andrew Larson1,4
1Departments of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL, USA; 2Department of Radiology, Northwestern University, Chicago, IL, USA; 3Department of Medicine, Northwestern University, Chicago, IL, USA; 4Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA
Transcatheter Intra-arterial Perfusion TRIP-MRI, using catheter-directed intraarterial (IA) contrast delivery, offers an objective method to intra-procedurally quantify tumor perfusion changes during TACE. The TRIP-MRI technique has previously been performed with 2D acquisitions in a combined clinical magnetic resonance/DSA unit (termed MR-IR unit) to monitor TACE. In this study, using a clinical MR-IR unit, we tested the hypothesis that 4D TRIP-MRI can be used to measure intra-procedural perfusion changes in liver tumors during TACE.