Abstract #2655

Ramani A, Hu C, Lu H, Ferris S, Szulc K, Jensen J, Helpern J

The purpose of this study was to detect differences in brain iron concentration in patients with Alzheimer disease, subjects with mild cognitive impairment and age-matched controls using magnetic field correlation (MFC) imaging, a novel quantitative MRI method for estimating brain iron. The MFC is a sensitive measure of the regional distribution of iron in the brain, and can be measured using an asymmetric spin echo sequence. We have previously provided feasibility of this method in-vivo. In this abstract, we have measured regional brain MFC values using parametric MFC maps and histogram analysis.