Abstract #1293

Parker J, Lenkinski R, Hatabu H, DeCamp M, Coute D, Kubo T, Ashiku S, Takahashi M, Kino A

The purpose of this study was to evaluate optimal breath instructions that provide less lung parenchyma movement, which can target small lung lesions during dynamic contrast-enhanced MRI scans. Our preliminary results indicate that dynamic contrasted-enhanced MRI of pulmonary nodule is feasible when a shallow breathing protocol is adopted. MR perfusion study of solitary pulmonary nodule using 3T MR system with high spatial and temporal resolution may provide a secondary characterizing method to distinguish benign from malignant nodules with minimal associated risks, thereby avoiding unnecessary intervention for benign lung nodules and associated mortality /morbidity.