Abstract #0858

Mistretta C, Lee J, Alexander A

This study examines the feasibility of a highly constrained reconstruction method for undersampled diffusion-weighted projection imaging with diffusion measurements obtained with high angular resolution. Simulations of a DTI experiment with projection imaging were performed. The highly constrained filter backprojection (HYPR) method demonstrated considerably reduced artifacts and increased SNR in the reconstructed images relative to standard filtered backprojection using an undersampling acceleration factor of 20.