Abstract #0480

Kreis R, Ith M, Benz T, Boesch C

Synopsis: A method is proposed that uses 1H-MRS to directly assess IMCL levels during exercise in eight male volunteers. Comparing IMCL usage of the tibialis anterior muscle during 3 hours of continuous or 3h of intermittent running revealed no significant difference, indicating that the 12 minutes breaks for MRS-measurements every half hour do not influence the IMCL metabolism. During both exercise sessions about 50% of the initial amount of IMCL was used. Measurements every 30 minutes revealed that only 5% of the total IMCL consumption was used during the initial 30 minutes, whereas 19% was used during each of the remaining bouts.