Abstract #0282

Granziera C, Wedeen V, Benner T, Wang R, Sorensen G

We studied a patient with a clinical picture of Wernick?s aphasia (fluent aphasia: impaired comprehension, naming and repetition) due to a lesion in the posterior region of the left superior temporal gyrus and involving the inferior part of the parietal lobe.Using DSI tractography, we could map the post-stroke remodelling of fibers located the stroke region and directly involved in the pathophysiology of the clinical picture (arcuate fasciculum). This work demonstrates that DSI could be used to study the connectivity involved in stroke recovery giving an anatomical insight into the complex mechanisms leading to functional improvement after an ischemic lesion.