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Abstract #8167

Neurovascular Consequences of Traumatic Brain Injury

David J. Mikulis1

1Toronto Western Hospital

Blood flow dysregulation is known to occur immediately after traumatic brain injury. Since neurovascular coupling is an essential component for maintaining the health of the neurovascular unit, impairment of this important regulatory mechanism can have significant implications on recovery from injury and may therefore be involved in the persistence of symptoms after injury. The ability to map dysregulation of blood flow using BOLD MRI cerebrovascular reactivity mapping offers the ability to investigate blood flow control providing a method to further understanding the relationship between post-injury blood flow derangements and recovery from injury.

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