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Abstract #8069

Preclinical Neural MRI for Basic Neuroscience

Afonso C. Silva1

1National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States

Anatomical and functional MRI, complemented by optical imaging methods and electrophysiology, have been at the forefront of unraveling the anatomical and functional organization of the brain. In this talk, we aim to show that high resolution anatomical MRI of the brain can be obtained with remarkable cytoarchitectonic detail, while fMRI can be used to study various sensory systems. Complimentary to MRI/fMRI, optical microscopy enables the simultaneous recording of neuronal activity from thousands of neurons with single cell spatial resolution. When combined together, the practical advantages of multi-modal neuroimaging techniques make preclinical imaging an invaluable avenue in neuroscience research.

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