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Abstract #8042

Quantitative Myocardial Perfusion

Hui Xue1, Michael S Hansen1, and Peter Kellman1

1National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, United States

Quantification of myocardial blood flow (MBF, in the unit of ml/min/g) is more objective to assess myocardial micro-circulation under rest and pharmaceutical or exercise stress condition and capture global flow reduction. Although perfusion quantification has been studies for the past 20 years, it is still not clear how to build a practical quantitative myocardial perfusion workflow. This syllabus reviews key components of such system and emphasizes on motion correction, intensity to Gd concentration conversion and Gd kinetics modelling. With recent developments more focusing on the automation and completeness of entire workflow, including fully automated processing and motion correction, the quantitative perfusion is becoming clinically practical.

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