Atherosclerosis, a systemic disease affecting large and medium sized arterial vessel walls is a leading cause of mortality in the world. MRI is quickly becoming the imaging modality of choice for visualizing atherosclerosis in the vessel wall. Atherosclerosis is evaluated in vivo by multi-contrast dark blood turbo spin echo imaging to evaluate plaque burden and composition. DCE- MRI can be used to evaluate plaque permeability. Recently, quantitative MR imaging in the form of T1 and T2 mapping of the vessel wall and on evaluating 4D flow, shear stress and circumferential strain in the arterial tree have become popular.