While the vast majority of MRS applications focus on the strong resonances of NAA, Cr, Cho and sometimes mIns and Glu+Gln, resonances from at least 15 neurochemicals, i.e., a comprehensive neurochemical profile are present in the spectrum. For detecting the small, weakly represented neurochemical resonances that underlie the typically detected large resonances such as NAA, Cr, Cho and mIns, options are: 1) to de-convolve all of the signals that are present or 2) to edit, i.e., to set the signal of interest apart (at least partially) from the others. Of course, there are advantages and disadvantages to each approach.
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