Akshay S Chaudhari1,2, Bragi Sveinsson1,3, Marcus T Alley1, Emily J McWalter1, Garry E Gold1,2, and Brian A Hargreaves1,2,3
1Radiology, Stanford University, Stanford, CA, United States, 2Bioengineering, Stanford University, Stanford, CA, United States, 3Electrical Engineering, Stanford University, Stanford, CA, United States
Quantitative MR imaging has the potential to provide information
regarding the biochemical state of tissues and to track biochemical changes
before the onset of morphological changes. However, with current MRI
techniques, it is challenging to obtain signal from tissues with short-T2
relaxation times in the knee, let alone to perform quantitative imaging on
them. Ultrashort echo-time double-echo in steady state (UTEDESS) is a pulse
sequence that offers echo times of 50μs, and high resolution imaging with high SNR
efficiencies. In this study, UTEDESS was also used to measure T2 relaxation
times of the menisci, tendons, and ligaments in human knees.