1Department and Institute of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan, 2Division of Nephrology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, 3Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, 4Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, 5Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 6Institute of BiomedicalSciences, Academic Sinica, Taipei, Taiwan, 7Department of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan