Abstract #4469

B1-insensitive high-resolution isotropic T2 mapping of the lumbar plexus with a T2-prepared 3D TSE

Dominik Weidlich¹, Barbara Cervantes¹, Nico Sollmann², Hendrik Kooijman³, Jan S. Kirschke⁴, Ernst J. Rummeny¹, Axel Haase⁵, and Dimitrios C. Karampinos¹

¹Department of Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany, ²Department of Neurosurgery, Technische Universität München, Munich, Germany, ³Philips Healthcare, Hamburg, Germany, ⁴Section of Neuroradiology, Technische Universität München, Munich, Germany, ⁵Zentralinstitut für Medizintechnik, Technische Universität München, Garching, Germany

T2 mapping is a great candidate for quantitatively assessing inflammatory changes in peripheral nerves. However, measuring T2 of the lumbar nerve roots is challenging because of the need for high isotropic resolution and the sensitivity of the region to transmit B1 inhomogeneities. The present work proposes a T2 preparation, based on a modified BIR-4 pulse, and combined with 3D TSE imaging for B1-insensitive high-resolution isotropic T2 mapping of the lumbar plexus. The feasibility of the method is shown in five healthy volunteers and a variation of T2 along the nerve root course is observed.

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