Sunil Koundal1,2, Sonia Gandhi1, Tanzeer Kaur2, and Subash Khushu1
1NMR Research Centre, Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi, India, 2Department of Biophysics, Panjab University, Chandigarh, India
High altitude
hypoxia poses a serious threat to human health. In the present study, rat were
exposed to acute simulated high altitude exposure which resulted in apparent
diffusion coefficient changes in brain regions including corpus callosum and
hippocampus. The study suggested the occurrence of vasogenic edema in corpus
callosum and delayed cytotoxic edema in hippocampus region of brain due to
acute high altitude exposure. This study has potential in setting new insights
to address high altitude related health problems effectively.
