Abstract #4417

White Matter Structural Alternations in Children with HIV Infection and Exposure

Marcin Jankiewicz¹, Paul A. Taylor^1,2,3, Martha Holmes¹, Mark F. Cotton⁴, Barbara Laughton⁴, Andre J.W. van der Kouwe⁵, and Ernesta M. Meintjes¹

¹MRC/UCT Medical Imaging Research Unit, Department of Human Biology, University of Cape Town, Cape Town, South Africa, ²Scientific and Statistical Computing Core, National Institutes of Health, Bethesda, MD, United States, ³African Institute for Mathematical Sciences, Muizenberg, South Africa, ⁴Children’s Infectious Diseases Clinical Research Unit, Department of Pediatrics and Child Health, Stellenbosch University, Cape Town, South Africa, ⁵Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States

In this work we examine WM alterations in HIV infected children at age 7 years and compare those who initiated ART before and after 12 weeks of age.

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