Abstract #4361

Differentiating radiation-induced brain necrosis from glioma recurrence: using 3-Dimensional arterial spin labeling and dynamic susceptibility contrast perfusion MR imaging

YULIN WANG¹ and LIN MA¹

¹Radiology, PLA General Hospital, beijing, China, People's Republic of

Perfusion made it possible to obtain measurements of vascularity within brain lesions. The vascularity of malignant tumor differs dramatically from that of radiation necrosis. Thus, tumor recurrence within irradiated lesions may be differentiated from regions of radiation necrosis with perfusion. 64 patients were prospectively entered into the study on the basis of the following criteria: previous treatment with radiation therapy after surgical resection for intraaxial tumors; new development of enhancing lesions within the radiation field. To compare 3D-ASL with DSC and to see whether 3D ASL-derived CBF values can be used as an alternative to DSC for their differentiation.

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