Hye-Young Heo1,2, Yi Zhang1, Dong-Hoon Lee1, Shanshan Jiang1, Xuna Zhao1, and Jinyuan Zhou1,2
1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 2F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States
Chemical exchange saturation transfer (CEST)
imaging is a unique contrast enhancement technique that enables the indirect
measurement of endogenous metabolites with water-exchangeable protons. The
measurement of a complete Z-spectrum using standard imaging acquisition scheme
is time consuming because a large number of the RF saturation frequency offset
followed by MR signal readout is inevitable to obtain the full Z-spectrum. In
this study, the feasibility of accelerated CEST imaging using combined CS and
SENSE technique (CS-SENSE) was demonstrated in healthy volunteers and glioma
patients at 3 T.
