Abstract #4224

Effect of a Low-Rank Denoising Algorithm on Quantitative MRI-Based Measures of Liver Fat and Iron

Brian C Allen¹, Felix Lugauer², Dominik Nickel², Lubna Bhatti¹, Randa A Dafalla¹, Brian M Dale³, Tracy A Jaffe¹, and Mustafa R Bashir^1,4

¹Radiology, Duke University Medical Center, Durham, NC, United States, ²MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, ³MR R&D Collaborations, Siemens Healthcare, Cary, NC, United States, ⁴Center for Advanced Magnetic Resonance Development, Duke University Medical Center, Durham, NC, United States

Applying the described low-rank denoising algorithm to a liver fat/iron quantification technique reduces image noise in PDFF and R2* maps without adversely affecting mean values of the quantitative measures or reader assessment of edge sharpness.

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