Abstract #4192

Diffusion kurtosis imaging can efficiently assess the glioma grade, cellular proliferation and survival

Rifeng Jiang¹, Jingjing Jiang¹, Jingjing Shi¹, Yihao Yao¹, Nanxi Shen¹, Changliang Su¹, Ju Zhang¹, and Wenzhen Zhu¹

¹Radiology, Tongji Hospital, Wuhan, China, People's Republic of

Compared with conventional diffusion metrics, the kurtosis metrics derived from DKI in the solid region of the tumors were better diagnostic factors in distinguishing HGGs from LGGs and identifying grade II, III and IV gliomas. The kurtosis metrics offered great potential to noninvasively predict the cellular proliferation of gliomas. DKI was also useful to evaluate the survival of glioma patients, and MK was a significant death risk in glioma patients.

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