Abstract #4156

Functional connectivity and neuroanatomical differences in a stress susceptible and resilient mouse model

Victoria X Wang¹, Caroline Menard², Cheuk Ying Tang³, Frances Marks¹, Johnny C Ng¹, Lazar Fleysher¹, Zahi A Fayad¹, and Scott Russo²

¹Radiology, Translational and Molecular Imaging Institute at Mount Sinai, New York, NY, United States, ²Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Radiology & Psychiatry, Translational and Molecular Imaging Institute at Mount Sinai, New York, NY, United States

We studied functional and structural connectivity in a stress susceptible and resilient mouse model using rsfMRI and DTI. We also investigated the integrity of the Blood Brain Barrier using Gd-DTPA. We found hyperactivity in the susceptible mice which had also several regions in the brain with compromised BBB. We also detected increased structural connectivity in the resilient mice.

This abstract and the presentation materials are available to members only; a login is required.

Join Here