The
hippocampus plays an important role in spatial and non-spatial episodic memory. Using DTI, a micro-structural probe sensitive to rapid neuroplasticity, and
the Morris water maze, we investigated spatial preference for place and time in
the hippocampus as revealed by changes in diffusion indices induced by learning
of a specific location in the maze and the overall training experience. We were
able to find a system-level mapping of space and time in the rat hippocampus.