Paul de Heer1, Maurice B Bizino2, Hildo J Lamb2, and Andrew G Webb1
1CJ Gorter Center, Radiology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands
Cardiac proton MR spectroscopy is a
challenging technique to perform in a reliable manner. In this study data
acquisition parameters are optimized in terms of signal-to-noise and
reproducibility. The optimal protocol was determined to be a PRESS localized
scan, local power optimization, pencil beam B0 shimming, a cardiac
trigger delay of 200 ms, MOIST water suppression and pencil beam navigator-based
respiratory compensation. With these parameters high intra- (r=1.000,
p<0.0001) and inter- (r=1.000, p=0.0004) session reproducibilities were
achieved. Bland-Altman analysis showed limits of agreement from -0.11 to 0.04 (intra)
and -0.15 to 0.9.
