Comparison of in vivo potassium, chloride and sodium TQ effects at 21.1 T
Victor Schepkin1, Andreas Neubauer2, Armin Nagel3, and Thomas Budinger4
1NHMFL/FSU, Tallahassee, FL, United States, 2University of Heidelberg, Mannheim, Germany, 3German Cancer Research Center (DKFZ), Heidelberg, Germany, 4Lawrence Berkeley National Laboratory/ UCB, Berkeley, CA, United States
A comparison of the TQ
MR signals without filtration from three in
vivo ions was performed in a rat head at 21.1 T using a time proportional
phase increment. A strong and competitive
binding of potassium relative to sodium was demonstrated and confirmed using agarose
samples. The TQ signal from in vivo chloride was the lowest. Our
results support a model that normal cells have similar ion binding in
intracellular and extracellular spaces. Visualization
of TQ magnetization was demonstrated using matching angular dependence of spherical harmonics and corresponding
irreducible tensors.
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