Arthur Coste1, Alexandre Vignaud1, Philippe Ciuciu1,2, Fawzi Boumezbeur1, Franck Mauconduit3, Alexis Amadon1, Sandro Romanzetti4, Denis Le Bihan1, and Cécile Lerman1
1MR Imaging and Spectroscopy Unit, NeuroSpin, Gif sur Yvette, France, 2Parietal, INRIA Saclay, Saclay, France, 3Siemens Healthcare, Saint Denis, France, 4University Clinic RWTH Aachen, Aachen, Germany
This work describes a novel method accounting for MR acquisition
properties (B0, B1+,B1-,T1,T2*)
to perform concentration measurements in the framework of in vitro Phosphorus MRI. Our pipeline uses a non-Cartesian 3D sequence
for efficient signal sampling and a wavelet regularized least square method for
reconstruction. We demonstrated within
an acceptable time for human experiment, for 5mm isotropic resolution, that we
are able to calibrate and measure absolute 31P concentrations.
