James Grist1, Martin J Graves1, Josh Kaggie1, Mary Mclean2, Frank Riemer1, and Ferdia A Gallager1
1Radiology, University of Cambridge, Cambridge, United Kingdom, 2Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom
Sodium T1
maps from three different Variable Flip Angle (VFA) methods were assessed
against Inversion Recovery (IR) data, showing that the estimated method of
slopes (eMOS) is superior to both linear and non-linear fitting methods in the
healthy brain. eMOS requires two flip angle data sets to produce volumetric T1
maps of the brain, in comparison to other techniques which require 4 or more data
sets to produce maps, and therefore allows for shortening of the overall time
spent scanning. Furthermore, T1 maps may also give further insight
in to the underlying tissue structure surrounding sodium nuclei.
