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Abstract #3913

Subcutaneous fat unsaturation is negatively associated with liver fat fraction

Christian Cordes1, Thomas Baum1, Julia Clavel2, Stefan Ruschke1, Michael Dieckmeyer1, Daniela Franz1, Hendrik Kooijman3, Ernst J. Rummeny1, Hans Hauner2, and Dimitrios Karampinos1

1Department of Diagnostic and Interventional Radiology, Technische Universitaet Muenchen, Munich, Germany, 2Else Kroener Fresenius Center for Nutritional Medicine, Technische Universitaet Muenchen, Munich, Germany, 3Philips Healthcare, Hamburg, Germany

Obesity, metabolic syndrome and diabetes are public health problems leading to increased morbidity and mortality. The present study performed fatty acid profiling of the abdominal adipose tissue by using MRS and found inverse correlations between SAT and liver fat fraction and regional distribution of adipose tissue (i.e. SAT and VAT volumes) assessed by chemical shift encoding-based water-fat MRI. This study allowed interesting insights into the obese phenotype and the reported findings may play an important role to identify different obese phenotypes, e.g. metabolically benign and insulin-resistant obese, which has clinical implications on patient treatment.

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