Abstract #3855

Agreement between MRE-estimated liver stiffness using 2D GRE and 2D SE-EPI pulse sequences at 3T

Adrija Mamidipalli¹, Jonathan Hooker¹, Nikolaus Szevrenyi¹, Alexandra Schlein¹, William Hauffe¹, Tanya Wolfson², Gavin Hamilton¹, Michael Middleton¹, and Claude Sirlin¹

¹Liver Imaging Group, UCSD, San Diego, CA, United States, ²Computational and Applied Statistics Laboratory, San Diego Supercomputer, UCSD, San Diego, CA, United States

In this study, agreement between MRE-estimated liver stiffness using 2D GRE and SE-EPI pulse sequences at 3T was examined in 30 adults with histology-confirmed nonalcoholic fatty liver disease (NAFLD) enrolled in a research registry. Results show that liver stiffness values obtained from both the sequences agree closely across a range of liver stiffness values for adults with NAFLD, although agreement tends to diverge at higher stiffness values. Differences at higher liver stiffness values were not explained by differences in image wave quality.

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