Kasper Winther Andersen1, Kristoffer H Madsen1, Tim B Dyrby1, and Hartwig R Siebner1,2
1Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark, Copenhagen, Denmark, 2Department of Neurology, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark
The basal ganglia is a
group of subcortical nuclei, which receives connections from almost the entire
cerebral cortex. Here, we investigated the involvement of the striatum, which
is the input structure of the basal ganglia, in a sequential finger movement task
using fMRI. Sixteen healthy controls performed finger sequences with different
complexities. Multi Voxel Pattern Analysis was used to discriminate the
distributed signal in striatum and cortex. We found that the distributed signals
in contra-lateral striatum are discriminative of the finger sequence performed,
which points to a significant role of the basal ganglia in the control of
finger sequences.
