Abstract #3734

Whole brain measurements of the hemodynamic response function variability during a finger tapping task at 7T show regional differences in hrf profiles.

Yohan Boillat¹, Rolf Gruetter^1,2,3, and Wietske van der Zwaag^1,4

¹Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ²Universite de Lausanne, Lausanne, Switzerland, ³Universite de Geneve, Geneva, Switzerland, ⁴Spinoza Centre for Neuroimaging, Amsterdam, Switzerland

The temporal properties of the BOLD response, including inter-trial variability, were studied using a 3D-EPI-CAIPI acquisition at 7T with TR=400ms. The HRFs of six different brain regions in the motor network were characterized, showing a reduced post-stimulus undershoot in the cerebellar regions of interest, as well as differences in peak height, with higher response amplitude in M1 than any other region and onset time, with the cerebellar lobule VIII response starting later than the other ROIs. Trial-to-trial variability was highest in CVIII and lowest in SI.

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