Abstract #3714

A Comparison between the UTE and PETRA Pulse Sequences for Fluorine-19 MRI at 3 Tesla

Roberto Colotti¹, Jean Delacoste¹, Giulia Ginami¹, Maxime Pellegrin², Tobias Kober^1,3,4, Yutaka Natsuaki⁵, David Grodzki⁶, Ulrich Flögel⁷, Matthias Stuber^1,8, and Ruud B. van Heeswijk¹

¹Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ²Division of Angiology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland, ³Advanced Clinical Imaging Technology, Siemens Healthcare IM BM PI, Lausanne, Switzerland, ⁴LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ⁵Siemens Medical Solutions, NAM USA DI MR COLLAB WE, Los Angeles, CA, United States, ⁶Siemens Healthcare GmbH, HC DI MR R&D PLH, Erlangen, Germany, ⁷Department of Cardiovascular Physiology, Heinrich Heine University, Düsseldorf, Germany, ⁸Center for Biomedical Imaging (CIBM), Lausanne, Switzerland

Fluorine-19 (¹⁹F) MRI of perfluorocarbon emulsions (PFCs) with multiresonant spectra is challenging due to destructive phase interference that leads to short T₂ relaxation times (<10 ms). Pulse sequences with very short echo times (≤ 100 µs) can be used to overcome this challenge. In this study, in vitro and in vivo ¹⁹F MRI obtained with both UTE and PETRA were acquired and quantitatively compared.

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